CPython has a myriad of ways for integrating with C/C++:

Create bindings for other languages without needing a compilation step (pure-Python solutions)

• cffi: Provides a way to call compiled C from Python without any compilation step (also compatible -- and fast -- with PyPy).

• ctypes: Builtin to Python it's a way to call C code from Python without any compilation step (also compatible with PyPy but slower than cffi).

Wrap C/C++ code and compile it to create bindings for existing C/C++ libraries.

• Cython: can compile Python code and mixed Cython/C/C++ code and can be used to create bindings for existing C/C++ libraries (the most "Pythonic" of the listed solutions).

• SWIG: Provides a way to wrap C/C++ code and compile it creating bindings (not only for Python, but also a many other languages).

• PyCXX: Provides a way to wrap C/C++ code and compile it creating bindings for Python.

• Boost.Python: Provides a way to wrap C/C++ code and compile it creating bindings for Python.

• SIP: used by PyQt to wrap Qt.

• shiboken: Used by PySide to wrap Qt.